The Buffalo Bills were defeated by the New England Patriots 29-26 at Highmark Stadium, with a late interception by Josh Allen thwarting a comeback and dropping Buffalo to 3-1 on the season. The loss highlighted ongoing defensive and situational issues that have plagued the team, despite bursts of offense and a strong late push. Keon Coleman emerged as a trusted target in the game, while coach Joe Brady emphasized the receiver's adaptability amid changes. The defeat prevents Buffalo from extending its lead in the AFC East and underscores a momentum stall after an early surge, with questions about whether the defense can fix recurring errors. The team faces a period of evaluation and adjustment as it moves forward into the next stretch of games.